By studying the chameleon model during inflation, we investigate whether it can be a successful inflationary model, wherein we employ the common typical potential usually used in the literature. Thus, in the context of the slow-roll approximations, we obtain the number of e-folding for the model to verify the ability of resolving the problems of standard big bang cosmology. Meanwhile, we apply the constraints on the form of the chosen potential and also on the equation of state parameter coupled to the scalar field. However, the results of the present analysis show that there is not much chance of having the chameleonic inflation. Hence, we suggest that if through some mechanism the chameleon model can be reduced to the standard inflationary model, then it may cover the whole era of the universe from the inflation up to the late time.

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