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A purity conjecture due to Grothendieck and Auslander–Goldman predicts that the Brauer group of a regular scheme does not change after removing a closed subscheme of codimension . The combination of several works of Gabber settles the conjecture except for some cases that concern -torsion Brauer classes in mixed characteristic . We establish the remaining cases by using the tilting equivalence for perfectoid rings. To reduce to perfectoids, we control the change of the Brauer group of the punctured spectrum of a local ring when passing to a finite flat cover.

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