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A theory of nonlinear signal propagation in multi-span wavelength division multiplexed coherent transmission systems that employ the semiconductor optical amplifier as in-line amplifiers is presented for the first time. The rigorous derivation, based on time-domain first-order perturbation theory, is developed in detail. The end result is the expressions for the signal-to-noise ratio of the received sampled photocurrent, including contributions from noise, fiber-induced nonlinear distortions, and amplified-induced nonlinear distortions.

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