Cluster integrable systems, q-Painleve equations and their quantization

We discuss the relation between the cluster integrable systems and $q$-difference Painlev'e equations. The Newton polygons corresponding to these integrable systems are all 16 convex polygons with a single interior point. The Painlev'e dynamics is interpreted as deautonomization of the discrete flows, generated by a sequence of the cluster quiver mutations, supplemented by permutations of quiver vertices. We also define quantum $q$-Painlev'e systems by quantization of the corresponding cluster variety. We present formal solution of these equations for the case of pure gauge theory using $q$-deformed conformal blocks or 5-dimensional Nekrasov functions. We propose, that quantum cluster structure of the Painlev'e system provides generalization of the isomonodromy/CFT correspondence for arbitrary central charge.