This paper presents the first search for non-resonant Higgs boson pair production in association with a top-quark pair () using proton-proton collision data collected with the ATLAS detector at the Large Hadron Collider. The data sample corresponds to an integrated luminosity of 196 fb, comprising 140 fb at a centre-of-mass energy of TeV and 56 fb at 13.6 TeV. The search targets three distinct final states expected from decays: (i) one lepton (electron or muon) with at least five -quarks, (ii) at least two -quarks accompanied by two leptons with the same electric charges or multiple leptons, and (iii) at least three -quarks with two photons. The production cross-section, relative to its Standard Model prediction, is measured to be . This result corresponds to a 95 confidence-level upper limit of 20 times the Standard Model prediction for the production cross-section, with an expected limit of 21. The Higgs effective field theory Wilson coefficient is also constrained at the same confidence level to the range of , compared with the expected range of .

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