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In this note we study the problem of characterizing the complex affine space via its automorphism group. We prove the following. Let be an irreducible quasi-projective -dimensional variety such that and are isomorphic as abstract groups. If is either quasi-affine and toric or is smooth with Euler characteristic and finite Picard group , then is isomorphic to . The main ingredient is the following result. Let be a smooth irreducible quasi-projective variety of dimension with finite . If admits a faithful -action for a prime and is not divisible by , then the identity component of the centralizer is a torus.

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