In this paper, we study the global regularity and sharp decay rates for the isentropic hypo-viscous compressible Navier-Stokes equations in 1D. Firstly, we prove the global stability for the small initial data near a stable equilibrium. Especially, we establish the global critical regularity in the Sobolev space with . Furthermore, by bootstrap argument, Fourier splitting method and energy method, we then establish the optimal time decay rates under the extra low-frequency smallness assumption. We find the energy is self-closed, which motivates us to obtain the existence of global large solutions for initial data with high regularity. By a pure energy method, we also derive the optimal time decay rates when . We find a phenomenon that still decays even if the initial data does not possess smallness. Notably, the low-frequency smallness assumption is removed in the case with .

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