We investigate the connection between semilinear elliptic PDEs with isolated singularities and stationary nonlinear Schrödinger equations with point interactions. In dimensions , we provide a detailed equivalence result between the two problems. As a consequence, this allows us to exploit a range of operator-theoretic and variational techniques, hitherto not explicitly explored in the context of singular solutions. By leveraging this approach, in the focusing case, we provide the existence of infinitely many singular solutions by applying the Ambrosetti-Rabinowitz theory to an action functional adapted to the point interaction. When and relying on a suitable uniqueness result, we also characterize positive solutions in terms of action ground states, and we show the existence of infinitely many singular, nodal solutions.

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