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We prove scaling invariant Gagliardo-Nirenberg type inequalities of the form involving fractional Sobolev norms with and Coulomb type energies with and . We establish optimal ranges of parameters for the validity of such inequalities and discuss the existence of the optimisers. In the special case our results include a new refinement of the fractional Sobolev inequality by a Coulomb term. We also prove that if the radial symmetry is taken into account, then the ranges of validity of the inequalities could be extended and such a radial improvement is possible if and only if .

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