We study the problem of selecting the shape parameter in Radial Basis function (RBF) interpolation using leave-one-out-cross-validation (LOOCV). Since the classical LOOCV formula requires repeated solves with a dense kernel matrix, we combine a Nyström approximation with the Woodbury identity to obtain an efficient surrogate objective that avoids large matrix inversions. Based on this reduced form, we compare a grid-based search with a gradient descent strategy and examine their behavior across different dimensions. Numerical experiments are performed in 1D, 2D, and 3D using the Inverse Multiquadratic RBF to illustrate the computational advantages of the approximation as well as the situations in which it may introduce additional sensitivity. These results show that the proposed acceleration makes LOOCV-based parameter tuning practical for larger datasets while preserving the qualitative behavior of the full method.

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