We study the second order nonlinear differential equation \begin{equation*} u"+ \sum_{i=1}^{m} \alpha_{i} a_{i}(x)g_{i}(u) - \sum_{j=0}^{m+1} \beta_{j} b_{j}(x)k_{j}(u) = 0, \end{equation*} where , are non-negative Lebesgue integrable functions defined in , and the nonlinearities are continuous, positive and satisfy suitable growth conditions, as to cover the classical superlinear equation , with . When the positive parameters are sufficiently large, we prove the existence of at least positive solutions for the Sturm-Liouville boundary value problems associated with the equation. The proof is based on the Leray-Schauder topological degree for locally compact operators on open and possibly unbounded sets. Finally, we deal with radially symmetric positive solutions for the Dirichlet problems associated with elliptic PDEs.

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