We characterize complete RNP-differentiability spaces as those spaces which
are rectifiable in terms of doubling metric measure spaces satisfying some
local -Poincar'e inequalities. This gives a full characterization of
spaces admitting a strong form of a differentiability structure in the sense of
Cheeger, and provides a partial converse to his theorem. The proof is based on
a new thickening' construction, which can be used to enlarge subsets into spaces admitting Poincar\'e inequalities. We also introduce a new notion of quantitative connectivity which characterizes spaces satisfying local Poincar\'e inequalities. This characterization is of independent interest, and has several applications separate from differentiability spaces. We resolve a question of Tapio Rajala on the existence of Poincar\'e inequalities for the class of $MCP(K, n)$-spaces which satisfy a weak Ricci-bound. We show that deforming a geodesic metric measure space by Muckenhoupt weights preserves the property of possessing a Poincar\'e inequality. Finally, the new condition allows us to show that many classes of weak, Orlicz and non-homogeneous Poincar\'e inequalities self-improve’ to classical -Poincar'e
inequalities for some , which is related to Keith’s and
Zhong’s theorem on self-improvement of Poincar'e inequalities.

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