Let be a simply connected simple algebraic group over , and its two opposite Borel subgroups, and the associated Weyl group. It is shown that the coordinate ring (, ) of the double Bruhat cell is isomorphic to the cluster algebra and the initial cluster variables of are the generalized minors by Berenstein, Fomin, Zelevinsky, Goodearl and Yakimov. In the case that a classical group is of type , or , we shall describe the non-trivial last initial cluster variables ( is some positive integer) of the cluster algebra in terms of monomial realization of Demazure crystals, where is the reduced double Bruhat cell of type . The relation between on and on is described as well. We also present the corresponding results for type though the results for all initial cluster variables have been obtained by ourselves.

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