Violations of symmetry and Lorentz invariance are searched for by studying interference effects in mixing and in mixing. Samples of and decays are recorded by the LHCb detector in proton–proton collisions at centre-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of 3 fb. No periodic variations of the particle-antiparticle mass differences are found, consistent with Lorentz invariance and symmetry. Results are expressed in terms of the Standard Model Extension parameter with precisions of and GeV for the and systems, respectively. With no assumption on Lorentz (non-)invariance, the -violating parameter in the system is measured for the first time and found to be $ e(z) = -0.022 \pm 0.033 \pm 0.005 m(z) = 0.004 \pm 0.011\pm 0.002$, where the first uncertainties are statistical and the second systematic.

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