Spin Physics through QCD Instantons

We review some aspects of spin physics where QCD instantons play an important role. In particular, their large contributions in semi-inclusive deep-inelastic scattering and polarized proton on proton scattering. We also review their possible contribution in the $\mathcal{P}$-odd pion azimuthal charge correlations in peripheral $AA$ scattering at collider energies.