The shell corrections and shell gaps in nuclei are systematically studied with the latest Weizs"acker-Skyrme (WS4) mass model. We find that most of asymmetric nuclei with (sub)-shell closures locate along the shell stability line (SSL), , which might be due to a strong correlation between neutrons and protons near Fermi surface. The double magicity of nuclei Si and Ni is predicted according to the corresponding shell gaps, shell corrections and nuclear deformations. The unmeasured super-heavy nuclei 118 and 120, with relatively large shell gaps and shell corrections, also locate along the SSL, whereas the traditional magic nucleus Fl evidently deviates from the line. The -decay energies of super-heavy nuclei with are simultaneously investigated by using the WS4 model together with the radial basis function corrections. For super-heavy nuclei with large shell corrections, the smallest -decay energy for elements , 117 and 118 in their isotope chains locates at rather than .

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