We consider fractional NLS with focusing power-type nonlinearity where and for $s \geq N/20 < \sigma \leq 2s/(N-2s)s < N/2$. We prove a general criterion for blowup of radial solutions in with for -supercritical and -critical powers . In addition, we study the case of fractional NLS posed on a bounded star-shaped domain in any dimension and subject to exterior Dirichlet conditions. In this setting, we prove a general blowup result without imposing any symmetry assumption on . For the blowup proof in , we derive a localized virial estimate for fractional NLS in , which uses Balakrishnan’s formula for the fractional Laplacian from semigroup theory. In the setting of bounded domains, we use a Pohozaev-type estimate for the fractional Laplacian to prove blowup.

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