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In this paper, we introduce a direct method of moving spheres for the nonlocal fractional Laplacian for , in which a key ingredient is the narrow region maximum principle. As immediate applications, we classify the non-negative solutions for a semilinear equation involving the fractional Laplacian in ; we prove a non-existence result for prescribing curvature equation on ; then by combining the direct method of moving planes and moving spheres, we establish a Liouville type theorem on the half Euclidean space. We expect to see more applications of this method to many other equations involving non-local operators.

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