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In this article we examine under which conditions symplectic homology with local coefficients of a unit disk bundle vanishes. For instance this is the case if the Hurewicz map is nonzero. As an application we prove finiteness of the -sensitive Hofer-Zehnder capacity of unit disk bundles in these cases. We also prove uniruledness for such cotangent bundles. Moreover, we find an obstruction to the existence of -space structures on general topological spaces, formulated in terms of local systems.

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