The semi-analytical expression for the renormalization group -function in the -scheme is obtained in the case of the gauge group. In the process of calculations we use the existing information about the three-loop perturbative approximation for the QCD static potential, evaluated in the -scheme. The comparison of the numerical values of the third and fourth coefficients for the QCD RG - functions in the gauge-independent - and -schemes and in minimal MOM scheme in the the Landau gauge is presented. The phenomenologically-oriented comparisons for the coefficients of expression for the -annihilation R-ratio in these schemes are presented. It is shown, that taking into account of these QCD contributions are of vital importance and lead to the drastic decrease of the scheme-dependence ambiguities of the fourth-order perturbative QCD approximations for the annihilation R-ratio for the number of active flavours, in particular. We demonstrate that in the case of QED with -types of leptons the coefficients of the -function are closely related to the ones of the Gell-Mann–Low -function and emphasise that they start to differ from each other at the fourth order due to the appearance of the extra -contribution in the V-scheme. The source of this extra correction is clarified. The general all-order QED relations between the coefficients of the - and -functions are discussed.

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