These notes deal with the mean-field approximation for equilibrium states of N-body systems in classical and quantum statistical mechanics. A general strategy for the justification of effective models based on statistical independence assumptions is presented in details. The main tools are structure theorems {`a} la de Finetti, describing the large N limits of admissible states for these systems. These rely on the symmetry under exchange of particles, due to their indiscernability. Emphasis is put on quantum aspects, in particular the mean-field approximation for the ground states of large bosonic systems, in relation with the Bose-Einstein condensation phenomenon. Topics covered in details include: the structure of reduced density matrices for large bosonic systems, Fock-space localization methods, derivation of effective energy functionals of Hartree or non-linear Schr{"o}dinger type, starting from the many-body Schr{"o}dinger Hamiltonian.

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