We study the properties of the potential overlap between two networks sharing the same set of nodes (a two-layer network) whose respective degree distributions are given. Defining the overlap coefficient as the Jaccard index, we derive upper bounds for the minimum and maximum overlap coefficient in terms of , and . We also present an algorithm based on cross-rewiring of links to obtain a two-layer network with any prescribed inside the permitted range. Finally, to illustrate the importance of the overlap for the dynamics of interacting contagious processes, we derive a mean-field model for the spread of an SIS epidemic with awareness against infection over a two-layer network, containing as a parameter. A simple analytical relationship between and the basic reproduction number follows. Stochastic simulations are presented to assess the accuracy of the upper bounds of and the predictions of the mean-field epidemic model.

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