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We study a generalized defocusing Hartree equation with nonlocal exchange potential and repulsive Hartree–Fock interaction. Using an inverse optimal problem (IOP) approach, we prove the existence and uniqueness of ground state solutions. Additionally, we establish the existence of principal solutions, their continuous dependence on parameters, and a dual variational formulation. The IOP method provides a systematic framework for addressing inverse problems in nonlocal Schrödinger operators and offers new insights into the structure of solutions for defocusing Hartree-type equations.

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