Disentangling reaction mechanisms in weakly bound nuclei remains a long-standing challenge, often compounded by the treatment of absorption as an incoherent sum of channel contributions. Within the Continuum-Discretized Coupled-Channels (CDCC) framework, we apply the generalized optical theorem [Nucl.\ Phys.\ A , 48 (2010)] and show that the total absorption cross section, , decomposes as , where is a coherent interference term between channel components. For the systems and fragment-target optical potentials considered, is negative and comparable in magnitude to the direct absorption terms. The off-diagonal imaginary couplings play a dual role, redistributing flux among channels and generating , which is required for flux-balance consistency. Calculations for and show that retaining the full non-diagonal coupling matrix substantially enhances breakup-channel absorption for heavy targets while reducing the total absorption through interference effects. Neglecting off-diagonal imaginary couplings therefore leads to a systematically biased physical picture, overestimating total absorption and severely underestimating breakup contributions, implying that experimental analyses based on incoherent-sum models inherit this bias. Full-coupling CDCC calculations are thus essential for consistent, mechanism-resolved extraction of absorption cross sections in weakly bound systems.

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