Lattice surgery is a leading approach for implementing fault-tolerant logical operations in surface code quantum computing, but compiling efficient lattice surgery layouts remains challenging. Existing compilers are largely circuit-centric and operate directly on gate sequences, limiting their ability to exploit the topological flexibility of merge-split operations and minimize space–time volume. We present TopoLS, a topology-centric compiler that uses ZX diagrams as an intermediate representation for lattice surgery compilation. TopoLS combines semantic-preserving ZX-level program transformations, including spider fusion and topology-aware slicing, with a Monte Carlo Tree Search (MCTS)-based synthesis procedure that constructs pipe-diagram embeddings by jointly optimizing placement and routing in 3D space–time. To scale to large circuits, TopoLS further introduces topology-aware partitioning that decomposes the compilation task into bounded subproblems and limits the routing frontier during embedding. Across evaluated benchmarks, TopoLS achieves an average reduction in space–time volume over prior circuit-centric compilers, with improvements ranging from to , and exhibits strong empirical scalability on large benchmark families. Compared with SAT-based formulations that become intractable on larger instances, TopoLS offers a practical end-to-end solution for optimized lattice surgery compilation. TopoLS has been integrated into the TQEC ecosystem, enabling downstream circuit-level simulation and resource estimation workflows.

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