We prove that the heat kernel associated to the Schr"odinger type operator
A:=(1+∣x∣α)Δ−∣x∣β satisfies the estimate k(t,x,y)≤c1eλ0tec2t−b1+∣y∣α(∣x∣∣y∣)−2N−1−4β−αe−β−α+22∣x∣2β−α+2e−β−α+22∣y∣2β−α+2 for
t>0,∣x∣,∣y∣≥1, where c1,c2 are positive constants and
b=β+α−2β−α+2 provided that N>2,α≥2
and β>α−2. We also obtain an estimate of the eigenfunctions of A.