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In this letter we analyze the effect of the spin dimensionality of a physical system in two mathematical formulations of the uncertainty principle: a generalized Heisenberg uncertainty relation valid for all antisymmetric N-fermion wavefunctions, and the Fisher-information- based uncertainty relation valid for all antisymmetric N-fermion wavefunctions of central potentials. The accuracy of these spin-modified uncertainty relations is examined for all atoms from Hydrogen to Lawrencium in a self-consistent framework.

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