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Measurements of inclusive charged-current cross section ratios on carbon, iron, and lead relative to scintillator are presented. Data for the analysis were collected by the fine-grained MINERvA detector in the NuMI beamline at Fermilab. This is the first direct measurement of nuclear dependence in neutrino scattering. The ratios show a depletion at low Bjorken and enhancement at large , both of which increase with the nucleon number of the target. The data exhibit trends not found in GENIE, a standard neutrino-nucleus event generator, or alternative models of nuclear modification to inelastic structure functions.

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