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We prove a conjecture of J.P. May concerning the nilpotence of elements in ring spectra with power operations, i.e., -ring spectra. Using an explicit nilpotence bound on the torsion elements in -local -algebras over , we reduce the conjecture to the nilpotence theorem of Devinatz, Hopkins, and Smith. As corollaries we obtain nilpotence results in various bordism rings including and , results about the behavior of the Adams spectral sequence for -ring spectra, and the non-existence of -ring structures on certain complex oriented ring spectra.

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