We study analytically the tracer particle mobility in single-file systems with distributed friction constants. Our system serves as a prototype for non-equilibrium, heterogeneous, strongly interacting Brownian systems. The long time dynamics for such a single-file setup belongs to the same universality class as the Rouse model with dissimilar beads. The friction constants are drawn from a density and we derive an asymptotically exact solution for the mobility distribution , where is the Laplace-space mobility. If is light-tailed (first moment exists) we find a self-averaging behaviour: with . When is heavy-tailed, for large we obtain moments where and no self-averaging. The results are corroborated by simulations.

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