Consider reaction-diffusion equation with and general inhomogeneous ignition reaction vanishing at . Typical solutions transition from to as time progresses, and we study them in the region where this transition occurs. Under fairly general qualitative hypotheses on we show that in dimensions , the Hausdorff distance of the super-level sets and remains uniformly bounded in time for each . Thus, remains uniformly in time close to the characteristic function of in the sense of Hausdorff distance of super-level sets. We also show that expands with average speed (over any long enough time interval) between the two spreading speeds corresponding to any -independent lower and upper bounds on . On the other hand, these results turn out to be false in dimensions $d\ge 4fd\le 3ud\ge 4$ involves construction of a counter-example for which this fails. Such results were before known for but are new for general non-periodic media in dimensions (some are also new for homogeneous and periodic media). They extend in a somewhat weaker sense to monostable, bistable, and mixed reaction types, as well as to transitions between general equilibria of the PDE, and to solutions not necessarily satisfying $u^-\le u\le u^+$.

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