In this work we present an analysis of flavor violating effects mediated by color sextet scalars, which arise naturally in left-right symmetric gauge theories based on SU(2)L \times SU(2)R \times SU(4)C group. The sextets, denoted here by \Delta{dd}, Delta{ud} and \Delta{uu}, couple to right–handed quarks. We delineate the constraints on these couplings arising from meson–anti-meson transitions and flavor changing weak decays. The sextet \Delta_{uu} mediates D^{0}-\bar{D}^{0} mixing via tree-level and box diagrams, and also mediates D --> K pi, pi pi decays. The sextets \Delta_{ud} and \Delta_{dd} mediate B_{d}^{0}-\bar{B}{d}^{0}, B{s}^{0}-\bar{B}_{s}^{0} and K^{0}-\bar{K}^{0} mixings as well as rare B and D meson decays. Our analysis shows that for coupling strengths of order 10^{-2}, the current experimental data requires the mass of these color sextets to exceed several TeV. These bounds are stronger than those obtained from direct LHC searches.

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