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This text develops a homotopy theory of 2-categories analogous to Grothendieck’s homotopy theory of categories developed in “Pursuing Stacks”. We define the notion of “basic localizer of 2-Cat”, 2-categorical generalization of Grothendieck’s notion of basic localizer, and we show that the homotopy theories of and 2- are equivalent in a remarkably strong sense: there is an isomorphism, compatible with localization, between the ordered classes of basic localizers of and 2-. It follows that weak homotopy equivalences in 2- can be characterised in an internal way, without mentioning topological spaces or simplicial sets.

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