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This article is concerned with the mathematical analysis of a class of a nonlinear fractional Schrodinger equations with a general Hartree-type integrand. We prove existence and uniqueness of global-in-time solutions to the associated Cauchy problem. Under suitable assumptions, we also prove the existence of standing waves using the method of concentration-compactness by studying the associated constrained minimization problem. Finally we show the orbital stability of standing waves which are the minimizers of the associate variational problem.

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