We construct solutions of the -dimensional Toda-Hirota equation (2dTHE) expressed by the Gelfand hypergeometric function (Gelfand HGF) on the Grassmannian of confluent or non-confluent type, which is labeled by a partition of . A system of hyperbolic equations in complex variables is obtained from the differential equations which form a main body of the Gelfand hypergeometric system and characterize the image of Radon transform. We use the Laplace sequence of the system of hyperbolic operators to find an elementary seed solution of the 2dTHE and then use the Bäcklund transformation to obtain higher solutions expressed in terms of Gelfand HGF. In constructing the Laplace sequence, the contiguity relations (operators) for the Gelfand HGF play an important role.

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