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We study multi-hadron systems with a single heavy quark (charm or bottom) in the limit of heavy quark mass. The spin degeneracy of the states with quantum numbers and for , known in a normal hadron, can be generalized to multi-hadron systems. The spin degeneracy is the universal phenomena for any multi-hadron systems with a single heavy quark, irrespective of their internal structures, including compact multi-quarks, hadronic molecules and exotic nuclei. We demonstrate the spin degeneracy in the hadronic systems formed by a heavy hadron effective theory; states with a , meson and a nucleon , and a meson in nuclear matter.

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