Despite its elementary definition, the self-avoiding walk (SAW) poses notoriously hard enumerative problems: exact connective constants are known for only a handful of infinite graphs, notably the honeycomb lattice \cite{ds}. We establish a general substitution principle for SAWs on infinite connected quasi-transitive cubic graphs under port-transitive vertex replacements, where each degree- vertex is replaced by a fixed finite three-port gadget. Writing for the associated two-port SAW series, we prove that for , equivalently is the unique solution of , thereby extending the Fisher-triangle relation of Grimmett–Li to arbitrary symmetric three-port gadgets. We also obtain the corresponding identity for bipartite graphs when one or both colour classes are transformed, and show that the critical exponents and (and under a standard regularity hypothesis) are invariant. For explicit gadget families, including complete-graph gadgets and Fisher-type constructions, these identities turn base graphs with known into infinite families of new quasi-transitive graphs whose connective constants are determined exactly as the unique roots of explicit algebraic equations.

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