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We consider a number of linear and non-linear boundary value problems involving generalized Schr"odinger equations. The model case is for with a bounded domain in . We use the Sobolev embedding theorem, and in some cases the Moser-Trudinger inequality and the Hardy-Sobolev inequality, to derive necessary conditions for the existence of nontrivial solutions. These conditions usually involve a lower bound for a product of powers of the norm of , the measure of , and a sharp Sobolev constant. In most cases, these inequalities are best possible.

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