The scalar strange-quark matrix element of the nucleon is computed with lattice QCD. A mixed-action scheme is used with domain-wall valence fermions computed on the staggered MILC sea-quark configurations. The matrix element is determined by making use of the Feynman-Hellmann theorem which relates this strange matrix element to the change in the nucleon mass with respect to the strange-quark mass. The final result of this calculation is m_s < N | s-bar s| N > = 49 ±10 ± 15 MeV and, correspondingly f_s = m_s < N | s-bar s |N > / m_N = 0.051 ± 0.011 ± 0.016. Given the lack of a quantitative comparison of this phenomenologically important quantity determined from various lattice QCD calculations, we take the opportunity to present such an average. The resulting conservative determination is f_s = 0.043 ± 0.011.

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