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In this paper, we investigate regularity criterion for the solution of the nematic liquid crystal flows in dimension three and two. We prove the solution is smooth up to time provided that there exists a positive constant such that (i) for n=3, |(u,\nabla d)|{L^{\infty}(0,T;\dot{B}^{-1}{\infty,\infty})}\leq \varepsilon_{0}, and (ii) for , |\nabla d|{L^{\infty}(0,T;\dot{B}^{-1}{\infty,\infty})}\leq \varepsilon_{0}.

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