Measurement of electrons from heavy quarks by PHENIX has been done for various collision species and energy.PHENIX has measured single electron spectra from heavy flavor decays in Au+Au collisions at GeV.The measurement of heavy flavor production for p + p in PHENIX has also been measured which provided the baseline for studying hot and dense matter effects in heavy ion reactions. In Au + Au we observe a strong suppression of single electron compared with scaled p + p which challenges radiative energy loss models because heavy quarksare expected to radiate less than light quarks. Measurements done in Cu + Cu collisions by PHENIX provide a measurement for species of intermediate size between p + p and Au + Au, while measurements in Au + Au collisions at GeV provide a measurement at lower energy.

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