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We discuss the heavy-quark contribution to deep inelastic scattering in the scheme with fixed flavors. Based on the recent ABM11 PDF analysis of world data for deep-inelastic scattering and fixed-target data for the Drell-Yan process with the running-mass definition for heavy quarks we show that fixed flavor number scheme is sufficient for describing the deep-inelastic-scattering data in the entire kinematic range. We compare with other PDF sets and comment on the implications for measuring the strong coupling constant .

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