We investigate the prospects for observing lepton number violation (LNV) by two units, , at the LHC within the leptoquark variant of the Zee Model, where Majorana neutrino masses arise radiatively at one-loop. The model features an doublet and singlet leptoquarks, whose interactions produce a distinctive same-sign dilepton plus jets signature, . Taking into account current experimental constraints, we identify the dominant production channels for this LNV signal and perform a detailed collider analysis. We find that the HL-LHC can probe leptoquark masses up to with this process. Observation of this signal would provide a direct test of LNV and would unambiguously establish the Majorana nature of neutrinos.

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