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We establish some interior regularity criterions of suitable weak solutions for the 3-D Navier-Stokes equations, which allow the vertical part of the velocity to be large under the local scaling invariant norm. As an application, we improve Ladyzhenskaya-Prodi-Serrin’s criterion and Escauriza-Seregin-\v{S}ver'{a}k’s criterion. We also show that if weak solution satisfies for some , then the number of singular points is finite.

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