In this paper, we study eigenvalues of the closed eigenvalue problem of the differential operator , which is introduced by Colding and Minicozzi in [4], on an -dimensional compact self-shrinker in . Estimates for eigenvalues of the differential operator are obtained. Our estimates for eigenvalues of the differential operator are sharp. Furthermore, we also study the Dirichlet eigenvalue problem of the differential operator on a bounded domain with a piecewise smooth boundary in an -dimensional complete self-shrinker in . For Euclidean space , the differential operator becomes the Ornstein-Uhlenbeck operator in stochastic analysis. Hence, we also give estimates for eigenvalues of the Ornstein-Uhlenbeck operator.

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