Nucleon scalar matrix elements with $N_f=2+1+1$ twisted mass fermions

We investigate scalar matrix elements of the nucleon using $N_f=2+1+1$ flavors of maximally twisted mass fermions at a fixed value of the lattice spacing of $a\approx 0.078\mathrm{f}\mathrm{m}$. We compute disconnected contributions to the relevant three-point functions using an efficient noise reduction technique. Using these methods together with an only multiplicative renormalization applicable for twisted mass fermions, allows us to obtain accurate results in the light and strange sector.