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This review examines data from hadron-nucleus collisions, primarily focusing on hard processes like Drell-Yan, heavy flavor and quarkonium production. It highlights observed modifications of particle yields as functions of momentum and rapidity, aiming to clarify the underlying QCD effects in cold nuclear matter (CNM). The paper outlines strategies for future experiments, including the Electron-Ion Collider (EIC), to distinguish between these effects. Key questions address the universality of suppression mechanisms and the role of non-perturbative physics, providing a road map for upcoming nuclear data.

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