The s-wave pion-kaon () scattering lengths at zero momentum are calculated in lattice QCD with sufficiently light quarks and strange quark at its physical value by the finite size formula. The light quark masses correspond to GeV. In the “Asqtad” improved staggered fermion formulation, we measure the four-point correlators for both isospin and 3/2 channels, and analyze the lattice simulation data at the next-to-leading order in the continuum three-flavor chiral perturbation theory, which enables us a simultaneous extrapolation of scattering lengths at physical point. We adopt a technique with the moving wall sources without gauge fixing to obtain the substantiable accuracy, moreover, for $I = 1/2$ channel, we employ the variational method to isolate the contamination from the excited states. Extrapolating to the physical point yields the scattering lengths as and $m_\pi a_{1/2} = 0.1827(37)I=3/2$ and 1/2 channels, respectively. Our simulation results for scattering lengths are in agreement with the experimental reports and theoretical predictions, and can be comparable with other lattice simulations. These simulations are carried out with MILC flavor gauge configurations at lattice spacing fm.

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