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We study the three-dimensional Cauchy problem for a non-isothermal compressible nematic liquid crystal system with far-field vacuum. By deriving refined energy estimates and exploiting the coupled structure of the equations, we establish the global existence and uniqueness of strong solutions, provided that the following scaling-invariant quantity is sufficiently small: In particular, our result identifies a new scaling-invariant quantity and does not impose additional restrictions on the viscosity coefficients, which improves previous work (Commun. Math. Sci. 21 (2023), 1455–1486).

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