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We present a complete systematic theoretical study of multifragmentation for asymmetric colliding nuclei for heavy-ion reactions in the energy range between 50 MeV/nucleon and 1000 MeV/nucleon by using isospin dependent quantum molecular dynamics (IQMD) model. We have observed an interesting outcome for asymmetric colliding nuclei. The comparison between the symmetric and asymmetric colliding nuclei for the isospin independent cross section and isospin dependent cross section has been studied. We have found the pronounced effect of different cross section and mass asymmetry on the nuclear reaction dynamics.

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